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BCOR Internal Tandem Duplication Expression in Neural Stem Cells Promotes Growth, Invasion, and Expression of PRC2 Targets

Central nervous system tumor with BCL6-corepressor internal tandem duplication (CNS-BCOR ITD) is a malignant entity characterized by recurrent alterations in exon 15 encoding the essential binding domain for the polycomb repressive complex (PRC). In contrast to deletion or truncating mutations seen...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Nakata, Satoshi, Yuan, Ming, Rubens, Jeffrey A., Kahlert, Ulf D., Maciaczyk, Jarek, Raabe, Eric H., Eberhart, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070097/
https://ncbi.nlm.nih.gov/pubmed/33920124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083913
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