Moderate Increase of Indoxyl Sulfate Promotes Monocyte Transition into Profibrotic Macrophages

OBJECTIVE: The uremic toxin Indoxyl-3-sulphate (IS), a ligand of Aryl hydrocarbon Receptor (AhR), raises in blood during early renal dysfunction as a consequence of tubular damage, which may be present even when eGFR is normal or only moderately reduced, and promotes cardiovascular damage and monocy...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Barisione, Chiara, Garibaldi, Silvano, Furfaro, Anna Lisa, Nitti, Mariapaola, Palmieri, Daniela, Passalacqua, Mario, Garuti, Anna, Verzola, Daniela, Parodi, Alessia, Ameri, Pietro, Altieri, Paola, Fabbi, Patrizia, Ferrar, Pier Francesco, Brunelli, Claudio, Arsenescu, Violeta, Balbi, Manrico, Palombo, Domenico, Ghigliotti, Giorgio
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2016
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771744/
https://ncbi.nlm.nih.gov/pubmed/26925780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149276
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