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Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice

In the current study, we examined the effects of depletion of phagocytes on the progression of Plasmodium yoelii 17XNL infection in mice. Strikingly, the depletion of phagocytic cells, including macrophages, with clodronate in the acute phase of infection significantly reduced peripheral parasitemia...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Terkawi, Mohamad Alaa, Nishimura, Maki, Furuoka, Hidefumi, Nishikawa, Yoshifumi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771365/
https://ncbi.nlm.nih.gov/pubmed/26755155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-15
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