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Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice

In the current study, we examined the effects of depletion of phagocytes on the progression of Plasmodium yoelii 17XNL infection in mice. Strikingly, the depletion of phagocytic cells, including macrophages, with clodronate in the acute phase of infection significantly reduced peripheral parasitemia...

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Foilsithe in:Infect Immun
Main Authors: Terkawi, Mohamad Alaa, Nishimura, Maki, Furuoka, Hidefumi, Nishikawa, Yoshifumi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771365/
https://ncbi.nlm.nih.gov/pubmed/26755155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-15
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