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Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice

In the current study, we examined the effects of depletion of phagocytes on the progression of Plasmodium yoelii 17XNL infection in mice. Strikingly, the depletion of phagocytic cells, including macrophages, with clodronate in the acute phase of infection significantly reduced peripheral parasitemia...

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Podrobná bibliografie
Vydáno v:Infect Immun
Hlavní autoři: Terkawi, Mohamad Alaa, Nishimura, Maki, Furuoka, Hidefumi, Nishikawa, Yoshifumi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771365/
https://ncbi.nlm.nih.gov/pubmed/26755155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-15
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