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Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice

In the current study, we examined the effects of depletion of phagocytes on the progression of Plasmodium yoelii 17XNL infection in mice. Strikingly, the depletion of phagocytic cells, including macrophages, with clodronate in the acute phase of infection significantly reduced peripheral parasitemia...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Terkawi, Mohamad Alaa, Nishimura, Maki, Furuoka, Hidefumi, Nishikawa, Yoshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771365/
https://ncbi.nlm.nih.gov/pubmed/26755155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-15
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