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Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice

In the current study, we examined the effects of depletion of phagocytes on the progression of Plasmodium yoelii 17XNL infection in mice. Strikingly, the depletion of phagocytic cells, including macrophages, with clodronate in the acute phase of infection significantly reduced peripheral parasitemia...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Terkawi, Mohamad Alaa, Nishimura, Maki, Furuoka, Hidefumi, Nishikawa, Yoshifumi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771365/
https://ncbi.nlm.nih.gov/pubmed/26755155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-15
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