Functional evaluation of therapeutic response for a mouse model of medulloblastoma

Medulloblastoma is an aggressive childhood cerebellar tumor. We recently reported a mouse model with conditional deletion of Patched1 gene that recapitulates many characteristics of the human medulloblastoma. Qualitative symptoms observed in the mouse model include irregular stride length, impaired...

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Gepubliceerd in:Transgenic Res
Hoofdauteurs: Samano, Aislynn K., Ohshima-Hosoyama, Sachiko, Whitney, Thomas G., Prajapati, Suresh I., Kilcoyne, Aoife, Taniguchi, Eri, Morgan, William W., Nelon, Laura D., Lin, Ai-Ling, Togao, Osamu, Jung, Inkyung, Rubin, Brian P., Nowak, Brent M., Duong, Timothy Q., Keller, Charles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770905/
https://ncbi.nlm.nih.gov/pubmed/20107895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-010-9361-1
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