A-803467, a tetrodotoxin-resistant sodium channel blocker, modulates ABCG2-mediated MDR in vitro and in vivo

ATP-binding cassette subfamily G member 2 (ABCG2) is a member of the ABC transporter superfamily proteins, which has been implicated in the development of multidrug resistance (MDR) in cancer, apart from its physiological role to remove toxic substances out of the cells. The diverse range of substra...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Anreddy, Nagaraju, Patel, Atish, Zhang, Yun-Kai, Wang, Yi-Jun, Shukla, Suneet, Kathawala, Rishil J., Kumar, Priyank, Gupta, Pranav, Ambudkar, Suresh V., Wurpel, John N. D., Chen, Zhe-Sheng, Guo, Huiqin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770772/
https://ncbi.nlm.nih.gov/pubmed/26515463
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