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In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity
Matrix metalloproteinase-2 (MMP2) is important in tumorigenesis, angiogenesis and tumor invasion. In this study, we investigated if the Cy5-tagged small immuno protein targeting the catalytic domain of human MMP2 (aMMP2-SIP) detects MMP2 in tumors non-invasively. For this purpose, we generated MMP2...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770595/ https://ncbi.nlm.nih.gov/pubmed/26923459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22198 |
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