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The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses

Recently, we have shown that the administration of the tumour-targeted antibody-based immunocytokine L19-IL2 after radiotherapy (RT) resulted in synergistic anti-tumour effect. Here we show that RT and L19-IL2 can activate a curative abscopal effect, with a long-lasting immunological memory. Ionizin...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Rekers, Nicolle H., Olivo Pimentel, Veronica, Yaromina, Ala, Lieuwes, Natasja G., Biemans, Rianne, Zegers, Catharina M. L., Germeraad, Wilfred T. V., Van Limbergen, Evert J., Neri, Dario, Dubois, Ludwig J., Lambin, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889197/
https://ncbi.nlm.nih.gov/pubmed/29632732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1414119
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