Multiple nucleic acid cleavage modes in divergent type III CRISPR systems

CRISPR-Cas is an RNA-guided adaptive immune system that protects bacteria and archaea from invading nucleic acids. Type III systems (Cmr, Csm) have been shown to cleave RNA targets in vitro and some are capable of transcription-dependent DNA targeting. The crenarchaeon Sulfolobus solfataricus has tw...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Zhang, Jing, Graham, Shirley, Tello, Agnes, Liu, Huanting, White, Malcolm F.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770243/
https://ncbi.nlm.nih.gov/pubmed/26801642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw020
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