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Multiple nucleic acid cleavage modes in divergent type III CRISPR systems

CRISPR-Cas is an RNA-guided adaptive immune system that protects bacteria and archaea from invading nucleic acids. Type III systems (Cmr, Csm) have been shown to cleave RNA targets in vitro and some are capable of transcription-dependent DNA targeting. The crenarchaeon Sulfolobus solfataricus has tw...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhang, Jing, Graham, Shirley, Tello, Agnes, Liu, Huanting, White, Malcolm F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770243/
https://ncbi.nlm.nih.gov/pubmed/26801642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw020
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