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Genome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools
The absolute and relative concentrations of the four dNTPs are key determinants of DNA replication fidelity, yet the consequences of altered dNTP pools on replication fidelity have not previously been investigated on a genome-wide scale. Here, we use deep sequencing to determine the types, rates and...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770217/ https://ncbi.nlm.nih.gov/pubmed/26609135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1298 |
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