Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model

Triple-negative breast cancer (TNBC) is a highly aggressive and recurrent type of breast carcinoma that is associated with poor patient prognosis. Because of the limited efficacy of current treatments, new therapeutic strategies need to be developed. The CXCR4-CXCL12 chemokine signaling axis guides...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Tulotta, Claudia, Stefanescu, Cristina, Beletkaia, Elena, Bussmann, Jeroen, Tarbashevich, Katsiaryna, Schmidt, Thomas, Snaar-Jagalska, B. Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770151/
https://ncbi.nlm.nih.gov/pubmed/26744352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.023275
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados