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Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model

Inhibition of VEGF signalling effectively suppresses localized tumour growth but accelerates tumour invasiveness and micrometastasis by unknown mechanisms. To study the dynamic and reciprocal interactions between tumour cells and their microenvironment during these processes, we established a xenogr...

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Autors principals: He, Shuning, Lamers, Gerda EM, Beenakker, Jan-Willem M, Cui, Chao, Ghotra, Veerander PS, Danen, Erik HJ, Meijer, Annemarie H, Spaink, Herman P, Snaar-Jagalska, B Ewa
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504093/
https://ncbi.nlm.nih.gov/pubmed/22374800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4013
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