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Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer
Resistance to human epidermal growth factor receptor 2 (HER2)-targeted therapies presents a major clinical problem. Although preclinical studies have identified a number of possible mechanisms, clinical validation has been difficult. This is most likely to reflect the reliance on cell-line models th...
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| Publicado no: | Dis Model Mech |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770148/ https://ncbi.nlm.nih.gov/pubmed/26721874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.023143 |
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