AZD8931, an equipotent, reversible inhibitor of signaling by epidermal growth factor receptor (EGFR), HER2, and HER3: preclinical activity in HER2 non-amplified inflammatory breast cancer models

INTRODUCTION: Epidermal growth factor receptor (EGFR) overexpression has been associated with prognostic and predictive value in inflammatory breast cancer (IBC). Epidermal growth factor receptor 2 (HER2) overexpression is observed at a higher rate in IBC compared with noninflammatory breast cancer....

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Bibliographic Details
Main Authors: Mu, Zhaomei, Klinowska, Teresa, Dong, Xiaoshen, Foster, Emily, Womack, Chris, Fernandez, Sandra V, Cristofanilli, Massimo
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061513/
https://ncbi.nlm.nih.gov/pubmed/24886365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-33-47
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