Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP(61)) levels

Brain-derived neurotrophic factor (BDNF) regulates synaptic strengthening and memory consolidation, and altered BDNF expression is implicated in a number of neuropsychiatric and neurodegenerative disorders. BDNF potentiates NMDAR function through activation of Fyn and ERK1/2. STriatal-Enriched prote...

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Gepubliceerd in:J Neurochem
Hoofdauteurs: Xu, Jian, Kurup, Pradeep, Azkona, Garikoitz, Baguley, Tyler D., Saavedra, Ana, Nairn, Angus C., Ellman, Jonathan A., Pérez-Navarro, Esther, Lombroso, Paul J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769989/
https://ncbi.nlm.nih.gov/pubmed/26316048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13295
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