PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining

The response to DNA double-strand breaks (DSBs) requires alterations in chromatin structure to promote the assembly of repair complexes on broken chromosomes. Non-homologous end-joining (NHEJ) is the dominant DSB repair pathway in human cells, but our understanding of how it operates in chromatin is...

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Publicado en:Mol Cell
Autores principales: Luijsterburg, Martijn S., de Krijger, Inge, Wiegant, Wouter W., Shah, Rashmi G., Smeenk, Godelieve, de Groot, Anton J.L., Pines, Alex, Vertegaal, Alfred C.O., Jacobs, Jacqueline J.L., Shah, Girish M., van Attikum, Haico
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769320/
https://ncbi.nlm.nih.gov/pubmed/26895424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.01.019
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