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DNA repair goes hip-hop: SMARCA and CHD chromatin remodellers join the break dance

Proper signalling and repair of DNA double-strand breaks (DSB) is critical to prevent genome instability and diseases such as cancer. The packaging of DNA into chromatin, however, has evolved as a mere obstacle to these DSB responses. Posttranslational modifications and ATP-dependent chromatin remod...

詳細記述

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書誌詳細
出版年:Philos Trans R Soc Lond B Biol Sci
主要な著者: Rother, Magdalena B., van Attikum, Haico
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577463/
https://ncbi.nlm.nih.gov/pubmed/28847822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0285
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