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DNA repair goes hip-hop: SMARCA and CHD chromatin remodellers join the break dance
Proper signalling and repair of DNA double-strand breaks (DSB) is critical to prevent genome instability and diseases such as cancer. The packaging of DNA into chromatin, however, has evolved as a mere obstacle to these DSB responses. Posttranslational modifications and ATP-dependent chromatin remod...
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| Pubblicato in: | Philos Trans R Soc Lond B Biol Sci |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577463/ https://ncbi.nlm.nih.gov/pubmed/28847822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0285 |
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