Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-Throughput Screen

Small-molecule agonists have been identified for TLR7, TLR8, TLR4 and TLR2 thus far, and chemotypes other than those of canonical ligands are yet to be explored for a number of innate immune receptors. The discovery of novel immunostimulatory molecules would enhance the repertoire of tools available...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Salyer, Alex C. D., Caruso, Giuseppe, Khetani, Karishma K., Fox, Lauren M., Malladi, Subbalakshmi S., David, Sunil A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769227/
https://ncbi.nlm.nih.gov/pubmed/26919709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149848
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