Hepcidin as a Major Component of Renal Antibacterial Defenses against Uropathogenic Escherichia coli

The iron-regulatory peptide hepcidin exhibits antimicrobial activity. Having previously shown hepcidin expression in the kidney, we addressed its role in urinary tract infection (UTI), which remains largely unknown. Experimental UTI was induced in wild-type (WT) and hepcidin-knockout (Hepc−/−) mice...

詳細記述

保存先:
書誌詳細
出版年:J Am Soc Nephrol
主要な著者: Houamel, Dounia, Ducrot, Nicolas, Lefebvre, Thibaud, Daher, Raed, Moulouel, Boualem, Sari, Marie-Agnes, Letteron, Philippe, Lyoumi, Said, Millot, Sarah, Tourret, Jerome, Bouvet, Odile, Vaulont, Sophie, Vandewalle, Alain, Denamur, Erick, Puy, Hervé, Beaumont, Carole, Gouya, Laurent, Karim, Zoubida
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2016
主題:
Basic Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769187/
https://ncbi.nlm.nih.gov/pubmed/26293821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014101035
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