Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Günther disease model

Hemolysis occurring in hematologic diseases is often associated with an iron loading anemia. This iron overload is the result of a massive outflow of hemoglobin into the bloodstream, but the mechanism of hemoglobin handling has not been fully elucidated. Here, in a congenital erythropoietic porphyri...

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Veröffentlicht in:Haematologica
Hauptverfasser: Millot, Sarah, Delaby, Constance, Moulouel, Boualem, Lefebvre, Thibaud, Pilard, Nathalie, Ducrot, Nicolas, Ged, Cécile, Lettéron, Philippe, de Franceschi, Lucia, Deybach, Jean Charles, Beaumont, Carole, Gouya, Laurent, De Verneuil, Hubert, Lyoumi, Saïd, Puy, Hervé, Karim, Zoubida
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286934/
https://ncbi.nlm.nih.gov/pubmed/28143953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.151621
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