Paroxetine-mediated GRK2 inhibition reverses cardiac dysfunction and remodeling after myocardial infarction

Heart failure (HF) is a disease of epidemic proportion and is associated with exceedingly high health care costs. G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptor (GPCR) kinase 2 (GRK2), which is up-regulated in the failing human heart, appears to play a critical role i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Transl Med
Egile Nagusiak: Schumacher, Sarah M., Gao, Erhe, Zhu, Weizhong, Chen, Xiongwen, Chuprun, J. Kurt, Feldman, Arthur M., Tesmer, John J. G., Koch, Walter J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768806/
https://ncbi.nlm.nih.gov/pubmed/25739765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa0154
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak