Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia

Idiopathic CD4 lymphopenia (ICL) is a rare syndrome defined by low CD4 T-cell counts (<300/µL) without evidence of HIV infection or other known cause of immunodeficiency. ICL confers an increased risk of opportunistic infections and has no established treatment. Interleukin-7 (IL-7) is fundamenta...

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Publicado en:Blood
Main Authors: Sheikh, Virginia, Porter, Brian O., DerSimonian, Rebecca, Kovacs, Stephen B., Thompson, William L., Perez-Diez, Ainhoa, Freeman, Alexandra F., Roby, Gregg, Mican, JoAnn, Pau, Alice, Rupert, Adam, Adelsberger, Joseph, Higgins, Jeanette, Bourgeois, Jeffrey S., Jensen, Stig M. R., Morcock, David R., Burbelo, Peter D., Osnos, Leah, Maric, Irina, Natarajan, Ven, Croughs, Therese, Yao, Michael D., Estes, Jacob D., Sereti, Irini
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Clinical Trials and Observations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768432/
https://ncbi.nlm.nih.gov/pubmed/26675348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-645077
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