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Humanized mouse models reveal an immunologic classification of idiopathic CD4 lymphocytopenia subtypes

Idiopathic CD4 lymphocytopenia (ICL) is a clinically heterogeneous immunodeficiency disorder defined by low numbers of circulating CD4(+) T cells and increased susceptibility to opportunistic infections. CD8(+) T cells, NK, and/or B cells may also be deficient in some patients. To delineate possible...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Perez-Diez, Ainhoa, Liu, Xiangdong, Sheikh, Virginia, Roby, Gregg, Stroncek, David F., Sereti, Irini
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675561/
https://ncbi.nlm.nih.gov/pubmed/31341106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127802
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