Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia

Idiopathic CD4 lymphopenia (ICL) is a rare syndrome defined by low CD4 T-cell counts (<300/µL) without evidence of HIV infection or other known cause of immunodeficiency. ICL confers an increased risk of opportunistic infections and has no established treatment. Interleukin-7 (IL-7) is fundamenta...

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Udgivet i:Blood
Main Authors: Sheikh, Virginia, Porter, Brian O., DerSimonian, Rebecca, Kovacs, Stephen B., Thompson, William L., Perez-Diez, Ainhoa, Freeman, Alexandra F., Roby, Gregg, Mican, JoAnn, Pau, Alice, Rupert, Adam, Adelsberger, Joseph, Higgins, Jeanette, Bourgeois, Jeffrey S., Jensen, Stig M. R., Morcock, David R., Burbelo, Peter D., Osnos, Leah, Maric, Irina, Natarajan, Ven, Croughs, Therese, Yao, Michael D., Estes, Jacob D., Sereti, Irini
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Clinical Trials and Observations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768432/
https://ncbi.nlm.nih.gov/pubmed/26675348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-645077
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