Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia

Idiopathic CD4 lymphopenia (ICL) is a rare syndrome defined by low CD4 T-cell counts (<300/µL) without evidence of HIV infection or other known cause of immunodeficiency. ICL confers an increased risk of opportunistic infections and has no established treatment. Interleukin-7 (IL-7) is fundamenta...

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Опубликовано в: :Blood
Главные авторы: Sheikh, Virginia, Porter, Brian O., DerSimonian, Rebecca, Kovacs, Stephen B., Thompson, William L., Perez-Diez, Ainhoa, Freeman, Alexandra F., Roby, Gregg, Mican, JoAnn, Pau, Alice, Rupert, Adam, Adelsberger, Joseph, Higgins, Jeanette, Bourgeois, Jeffrey S., Jensen, Stig M. R., Morcock, David R., Burbelo, Peter D., Osnos, Leah, Maric, Irina, Natarajan, Ven, Croughs, Therese, Yao, Michael D., Estes, Jacob D., Sereti, Irini
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2016
Предметы:
Clinical Trials and Observations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768432/
https://ncbi.nlm.nih.gov/pubmed/26675348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-645077
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