Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA

Lipid-like nanoparticles (LLNs) have shown great potential for RNA delivery. Lipid-like compounds are key components in LLNs. In this study, we investigated the effects of local structural transformation of lipid-like compounds on delivery of messenger RNA. Our results showed that position change of...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Li, Bin, Luo, Xiao, Deng, Binbin, Giancola, JoLynn B., McComb, David W., Schmittgen, Thomas D., Dong, Yizhou
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768262/
https://ncbi.nlm.nih.gov/pubmed/26916931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22137
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