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Preparation and Optimization of Lipid-Like Nanoparticles for mRNA Delivery
Lipid-like nanoparticles (LLNs) have shown great promise for nucleic acid delivery. Recently, we have developed N(1),N(3),N(5)-tris(2-aminoethyl)benzene-1,3,5-tricarboxamide (TT) derived lipid-like compounds, formulated them into TT LLNs for mRNA delivery, and applied an orthogonal array design to f...
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| Udgivet i: | Methods Mol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5921050/ https://ncbi.nlm.nih.gov/pubmed/28730441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7138-1_13 |
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