Heterologous Production of the Marine Myxobacterial Antibiotic Haliangicin and Its Unnatural Analogues Generated by Engineering of the Biochemical Pathway

Despite their fastidious nature, marine myxobacteria have considerable genetic potential to produce novel secondary metabolites. The marine myxobacterium Haliangium ochraceum SMP-2 produces the antifungal polyketide haliangicin (1), but its productivity is unsatisfactory. The biosynthetic gene clust...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Sun, Yuwei, Feng, Zhiyang, Tomura, Tomohiko, Suzuki, Akira, Miyano, Seishi, Tsuge, Takashi, Mori, Hitoshi, Suh, Joo-Won, Iizuka, Takashi, Fudou, Ryosuke, Ojika, Makoto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768178/
https://ncbi.nlm.nih.gov/pubmed/26915413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22091
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