Heterologous Production of the Marine Myxobacterial Antibiotic Haliangicin and Its Unnatural Analogues Generated by Engineering of the Biochemical Pathway

Despite their fastidious nature, marine myxobacteria have considerable genetic potential to produce novel secondary metabolites. The marine myxobacterium Haliangium ochraceum SMP-2 produces the antifungal polyketide haliangicin (1), but its productivity is unsatisfactory. The biosynthetic gene clust...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Sun, Yuwei, Feng, Zhiyang, Tomura, Tomohiko, Suzuki, Akira, Miyano, Seishi, Tsuge, Takashi, Mori, Hitoshi, Suh, Joo-Won, Iizuka, Takashi, Fudou, Ryosuke, Ojika, Makoto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768178/
https://ncbi.nlm.nih.gov/pubmed/26915413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22091
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