Coagulation factor XI promotes distal platelet activation and single platelet consumption in the bloodstream under shear flow

OBJECTIVE: Coagulation factor XI (FXI) has been shown to contribute to thrombus formation on collagen or tissue factor (TF)-coated surfaces in vitro and in vivo by enhancing thrombin generation. Whether the role of the intrinsic pathway of coagulation is restricted to the local site of thrombus form...

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Detaylı Bibliyografya
Yayımlandı:Arterioscler Thromb Vasc Biol
Asıl Yazarlar: Zilberman-Rudenko, Jevgenia, Itakura, Asako, Wiesenekker, Chantal P., Vetter, Ralf, Maas, Coen, Gailani, David, Tucker, Erik I., Gruber, András, Gerdes, Christoph, McCarty, Owen J. T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767639/
https://ncbi.nlm.nih.gov/pubmed/26769048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307034
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