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Coagulation factor XI promotes distal platelet activation and single platelet consumption in the bloodstream under shear flow
OBJECTIVE: Coagulation factor XI (FXI) has been shown to contribute to thrombus formation on collagen or tissue factor (TF)-coated surfaces in vitro and in vivo by enhancing thrombin generation. Whether the role of the intrinsic pathway of coagulation is restricted to the local site of thrombus form...
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Publicado no: | Arterioscler Thromb Vasc Biol |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767639/ https://ncbi.nlm.nih.gov/pubmed/26769048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307034 |
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