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Coagulation factor XI promotes distal platelet activation and single platelet consumption in the bloodstream under shear flow

OBJECTIVE: Coagulation factor XI (FXI) has been shown to contribute to thrombus formation on collagen or tissue factor (TF)-coated surfaces in vitro and in vivo by enhancing thrombin generation. Whether the role of the intrinsic pathway of coagulation is restricted to the local site of thrombus form...

詳細記述

保存先:
書誌詳細
出版年:Arterioscler Thromb Vasc Biol
主要な著者: Zilberman-Rudenko, Jevgenia, Itakura, Asako, Wiesenekker, Chantal P., Vetter, Ralf, Maas, Coen, Gailani, David, Tucker, Erik I., Gruber, András, Gerdes, Christoph, McCarty, Owen J. T.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767639/
https://ncbi.nlm.nih.gov/pubmed/26769048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307034
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