Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers

BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) are rare and frequently lethal tumors that so far have not been subjected to comprehensive genetic characterization. METHODS. We performed next-generation sequencing of 341 cancer genes from 117 patient-deriv...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Landa, Iñigo, Ibrahimpasic, Tihana, Boucai, Laura, Sinha, Rileen, Knauf, Jeffrey A., Shah, Ronak H., Dogan, Snjezana, Ricarte-Filho, Julio C., Krishnamoorthy, Gnana P., Xu, Bin, Schultz, Nikolaus, Berger, Michael F., Sander, Chris, Taylor, Barry S., Ghossein, Ronald, Ganly, Ian, Fagin, James A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767360/
https://ncbi.nlm.nih.gov/pubmed/26878173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85271
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