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Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers

BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) are rare and frequently lethal tumors that so far have not been subjected to comprehensive genetic characterization. METHODS. We performed next-generation sequencing of 341 cancer genes from 117 patient-deriv...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Landa, Iñigo, Ibrahimpasic, Tihana, Boucai, Laura, Sinha, Rileen, Knauf, Jeffrey A., Shah, Ronak H., Dogan, Snjezana, Ricarte-Filho, Julio C., Krishnamoorthy, Gnana P., Xu, Bin, Schultz, Nikolaus, Berger, Michael F., Sander, Chris, Taylor, Barry S., Ghossein, Ronald, Ganly, Ian, Fagin, James A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767360/
https://ncbi.nlm.nih.gov/pubmed/26878173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85271
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