Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers

BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) are rare and frequently lethal tumors that so far have not been subjected to comprehensive genetic characterization. METHODS. We performed next-generation sequencing of 341 cancer genes from 117 patient-deriv...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Landa, Iñigo, Ibrahimpasic, Tihana, Boucai, Laura, Sinha, Rileen, Knauf, Jeffrey A., Shah, Ronak H., Dogan, Snjezana, Ricarte-Filho, Julio C., Krishnamoorthy, Gnana P., Xu, Bin, Schultz, Nikolaus, Berger, Michael F., Sander, Chris, Taylor, Barry S., Ghossein, Ronald, Ganly, Ian, Fagin, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767360/
https://ncbi.nlm.nih.gov/pubmed/26878173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85271
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