Genomic alterations in fatal forms of non-anaplastic thyroid cancer: Identification of MED12 and RBM10 as novel thyroid cancer genes associated with tumor virulence

PURPOSE: Patients with anaplastic thyroid cancer have a very high death rate. In contrast, deaths from non-anaplastic thyroid cancer are much less common. The genetic alterations in fatal non-anaplastic thyroid cancers have not been reported. EXPERIMENTAL DESIGN: We performed next-generation sequenc...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Ibrahimpasic, Tihana, Xu, Bin, Landa, Iñigo, Dogan, Snjezana, Middha, Sumit, Seshan, Venkatraman, Deraje, Shyam, Carlson, Diane L, Migliecci, Jocelyn, Knauf, Jeffrey A., Untch, Brian, Berger, Michael F., Morris, Luc, Tuttle, R. Michael, Chan, Timothy, Fagin, James A., Ghossein, Ronald, Ganly, Ian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626586/
https://ncbi.nlm.nih.gov/pubmed/28634282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1183
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