Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs

The transcription factor GATA3 is essential for the genesis and maturation of the T cell lineage, and GATA3 dysregulation has pathological consequences. Previous studies have shown that GATA3 function in T cell development is regulated by multiple signaling pathways and that the Notch nuclear effect...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Ohmura, Sakie, Mizuno, Seiya, Oishi, Hisashi, Ku, Chia-Jui, Hermann, Mary, Hosoya, Tomonori, Takahashi, Satoru, Engel, James Douglas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767349/
https://ncbi.nlm.nih.gov/pubmed/26808502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83894
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