PKCδ inhibition normalizes the wound-healing capacity of diabetic human fibroblasts

Abnormal fibroblast function underlies poor wound healing in patients with diabetes; however, the mechanisms that impair wound healing are poorly defined. Here, we evaluated fibroblasts from individuals who had type 1 diabetes (T1D) for 50 years or more (Medalists, n = 26) and from age-matched contr...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Khamaisi, Mogher, Katagiri, Sayaka, Keenan, Hillary, Park, Kyoungmin, Maeda, Yasutaka, Li, Qian, Qi, Weier, Thomou, Thomas, Eschuk, Danielle, Tellechea, Ana, Veves, Aris, Huang, Chenyu, Orgill, Dennis Paul, Wagers, Amy, King, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767341/
https://ncbi.nlm.nih.gov/pubmed/26808499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82788
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