Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors

BACKGROUND: Identification of genetic changes in CNS tumors is important for the appropriate clinical management of patients. Our objective was to develop a next-generation sequencing (NGS) assay for simultaneously detecting the various types of genetic alterations characteristic for adult and pedia...

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Vydáno v:Neuro Oncol
Hlavní autoři: Nikiforova, Marina N., Wald, Abigail I., Melan, Melissa A., Roy, Somak, Zhong, Shan, Hamilton, Ronald L., Lieberman, Frank S., Drappatz, Jan, Amankulor, Nduka M., Pollack, Ian F., Nikiforov, Yuri E., Horbinski, Craig
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Clinical Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767245/
https://ncbi.nlm.nih.gov/pubmed/26681766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov289
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