NT-03 DRAMATIC RESPONSE INDUCED BY VEMURAFENIB IN A BRAF V600E-MUTATED BEVACIZUMAB REFRACTORY GLIOBLASTOMA

A significant number of patients with high-grade gliomas do not respond to standard therapy. For relapsed bevacizumab refractory Glioblastoma (GBM), no effective treatment options exist. Recently, BRAF V600 mutations have been recognized in higher frequency in younger patients with epithelioid GBM (...

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Main Authors: Arvanitis, Leonidas, Marchioli, Carmine, Flickinger, John, Pritchard, Ashley, Engh, Johnathan, Amankulor, Nduka, Lieberman, Frank, Nikiforova, Marina, Murdoch, Geoffrey, Drappatz, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218440/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou265.3
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