Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors

BACKGROUND: Identification of genetic changes in CNS tumors is important for the appropriate clinical management of patients. Our objective was to develop a next-generation sequencing (NGS) assay for simultaneously detecting the various types of genetic alterations characteristic for adult and pedia...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Nikiforova, Marina N., Wald, Abigail I., Melan, Melissa A., Roy, Somak, Zhong, Shan, Hamilton, Ronald L., Lieberman, Frank S., Drappatz, Jan, Amankulor, Nduka M., Pollack, Ian F., Nikiforov, Yuri E., Horbinski, Craig
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Clinical Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767245/
https://ncbi.nlm.nih.gov/pubmed/26681766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov289
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