Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors

BACKGROUND: Identification of genetic changes in CNS tumors is important for the appropriate clinical management of patients. Our objective was to develop a next-generation sequencing (NGS) assay for simultaneously detecting the various types of genetic alterations characteristic for adult and pedia...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Nikiforova, Marina N., Wald, Abigail I., Melan, Melissa A., Roy, Somak, Zhong, Shan, Hamilton, Ronald L., Lieberman, Frank S., Drappatz, Jan, Amankulor, Nduka M., Pollack, Ian F., Nikiforov, Yuri E., Horbinski, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767245/
https://ncbi.nlm.nih.gov/pubmed/26681766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov289
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