Targeted Next-Generation Sequencing Panel (ThyroSeq) for Detection of Mutations in Thyroid Cancer

OBJECTIVES: Next-generation sequencing (NGS) allows for high-throughput sequencing analysis of large regions of the human genome. We explored the use of targeted NGS for simultaneous testing for multiple mutations in thyroid cancer. DESIGN: A custom panel (ThyroSeq) was designed to target 12 cancer...

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Hlavní autoři: Nikiforova, Marina N., Wald, Abigail I., Roy, Somak, Durso, Mary Beth, Nikiforov, Yuri E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2013
Témata:
JCEM Online: Advances in Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816258/
https://ncbi.nlm.nih.gov/pubmed/23979959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-2292
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