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An Smc3 Acetylation Cycle Is Essential for Establishment of Sister Chromatid Cohesion

Sister chromatid cohesion is thought to involve entrapment of sister DNAs by a tripartite ring composed of the cohesin subunits Smc1, Smc3, and Scc1. Establishment of cohesion during S phase depends on acetylation of Smc3’s nucleotide-binding domain (NBD) by the Eco1 acetyl transferase. It is destro...

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Publicado en:Mol Cell
Main Authors: Beckouët, Frederic, Hu, Bin, Roig, Maurici B., Sutani, Takashi, Komata, Makiko, Uluocak, Pelin, Katis, Vittorio L., Shirahige, Katsuhiko, Nasmyth, Kim
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766734/
https://ncbi.nlm.nih.gov/pubmed/20832721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.008
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