Local breathing and global unfolding in hydrogen exchange of barnase and its relationship to protein folding pathways.
We have measured the rate constants for exchange of amide protons in 15N-labeled wild-type barnase and a disulfide mutant that is more stable by 2 kcal.mol-1. The relative rate constants for exchange for wild type and mutant should reflect the changes in the equilibrium constants for local or global...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.9837 |
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