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The association of endoplasmic reticulum aminopeptidase-1 (ERAP-1) with Familial Mediterranean Fever (FMF)

BACKGROUND: The ERAP1 gene cleaves the receptors and reduces their ability to transmit chemical signals to the cell that affect the process of inflammation and, secondly, it cleaves many types of proteins into small peptides that are recognized by the immune system. OBJECTIVE: ERAP-1 gene mutations...

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Bibliografiske detaljer
Udgivet i:United European Gastroenterol J
Main Authors: Sezgin, Gülbüz, Dabak, Reşat, Kaya, Fatih Oner, Kotevoglu, Nurdan, Uygur-Bayramiçli, Oya, Nalbant, Selim
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766545/
https://ncbi.nlm.nih.gov/pubmed/26966528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640615584536
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