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The association of endoplasmic reticulum aminopeptidase-1 (ERAP-1) with Familial Mediterranean Fever (FMF)

BACKGROUND: The ERAP1 gene cleaves the receptors and reduces their ability to transmit chemical signals to the cell that affect the process of inflammation and, secondly, it cleaves many types of proteins into small peptides that are recognized by the immune system. OBJECTIVE: ERAP-1 gene mutations...

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Detalhes bibliográficos
Publicado no:United European Gastroenterol J
Main Authors: Sezgin, Gülbüz, Dabak, Reşat, Kaya, Fatih Oner, Kotevoglu, Nurdan, Uygur-Bayramiçli, Oya, Nalbant, Selim
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766545/
https://ncbi.nlm.nih.gov/pubmed/26966528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640615584536
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