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The association of endoplasmic reticulum aminopeptidase-1 (ERAP-1) with Familial Mediterranean Fever (FMF)

BACKGROUND: The ERAP1 gene cleaves the receptors and reduces their ability to transmit chemical signals to the cell that affect the process of inflammation and, secondly, it cleaves many types of proteins into small peptides that are recognized by the immune system. OBJECTIVE: ERAP-1 gene mutations...

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Publicat a:United European Gastroenterol J
Autors principals: Sezgin, Gülbüz, Dabak, Reşat, Kaya, Fatih Oner, Kotevoglu, Nurdan, Uygur-Bayramiçli, Oya, Nalbant, Selim
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766545/
https://ncbi.nlm.nih.gov/pubmed/26966528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640615584536
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