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The association of endoplasmic reticulum aminopeptidase-1 (ERAP-1) with Familial Mediterranean Fever (FMF)

BACKGROUND: The ERAP1 gene cleaves the receptors and reduces their ability to transmit chemical signals to the cell that affect the process of inflammation and, secondly, it cleaves many types of proteins into small peptides that are recognized by the immune system. OBJECTIVE: ERAP-1 gene mutations...

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Publicado en:United European Gastroenterol J
Autores principales: Sezgin, Gülbüz, Dabak, Reşat, Kaya, Fatih Oner, Kotevoglu, Nurdan, Uygur-Bayramiçli, Oya, Nalbant, Selim
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766545/
https://ncbi.nlm.nih.gov/pubmed/26966528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640615584536
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