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The association of endoplasmic reticulum aminopeptidase-1 (ERAP-1) with Familial Mediterranean Fever (FMF)

BACKGROUND: The ERAP1 gene cleaves the receptors and reduces their ability to transmit chemical signals to the cell that affect the process of inflammation and, secondly, it cleaves many types of proteins into small peptides that are recognized by the immune system. OBJECTIVE: ERAP-1 gene mutations...

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Dettagli Bibliografici
Pubblicato in:United European Gastroenterol J
Autori principali: Sezgin, Gülbüz, Dabak, Reşat, Kaya, Fatih Oner, Kotevoglu, Nurdan, Uygur-Bayramiçli, Oya, Nalbant, Selim
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766545/
https://ncbi.nlm.nih.gov/pubmed/26966528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640615584536
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