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Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1
Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an essential component of the immune system, because it trims peptide precursors and generates the N--restricted epitopes. To examine ERAP1's unique properties of length- and sequence-dependent processing of antigen precursors, we report a 2.3 Å...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240994/ https://ncbi.nlm.nih.gov/pubmed/22355701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00186 |
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